Interactions Between Drugs and Food. 8/2016

Published by AIDSMAP

The following is an overview of dietary requirements for currently available HIV drugs. When you are prescribed a new drug you should be given written information about how to take it, including information about dietary restrictions.

Ask your doctor, pharmacist or dietitian if you would like any further information about your diet and HIV drugs.

Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs)

 

Food requirements

abacavir (Ziagen)

May be taken with or without food.

emtricitabine (Emtriva)

May be taken with or without food.

lamivudine (Epivir)

May be taken with or without food.

tenofovir disoproxil (Viread)

Take with food.

zidovudine (Retrovir)

May be taken with or without food, though taking with food may reduce nausea.

Combination pills

 

Food requirements

Atripla (efavirenz, emtricitabine and tenofovir disoproxil combined)

Take on an empty stomach (preferably at bedtime), to reduce the incidence of side-effects (particularly avoid taking it soon after a high-fat meal as this increases the risk of side-effects).

lamivudine and zidovudine (combined – sometimes called Combivir)

May be taken with or without food, although taking with food may reduce nausea.

Descovy (tenofovir alafenamide and emtricitabine combined)

Take with or without food.

Eviplera (rilpivirine, emtricitabine and tenofovir disoproxil combined)

Take with food.

Genvoya (elvitegravir, emtricitabine, tenofovir alafenamide and cobicistat, a boosting agent)

Take with food.

Kivexa (lamivudine and abacavir combined)

May be taken with or without food.

Stribild (elvitegravir, emtricitabine, tenofovir disoproxil and cobicistat, a boosting agent)

Take with food.

Triumeq (dolutegravir, abacavir and lamivudine combined)

May be taken with or without food.

Trizivir (zidovudine, lamivudine and abacavir combined)

May be taken with or without food.

Truvada (tenofovir disoproxil and emtricitabine combined)

Take with or after food.

Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

 

Food requirements

efavirenz (Sustiva)

Take on an empty stomach (preferably at bedtime), to reduce the incidence of side-effects (particularly avoid taking it soon after a high-fat meal as this increases the risk of side-effects).

etravirine (Intelence)

Take with or after food (within two hours after a main meal or within half an hour after a snack).

nevirapine (Viramune and Viramune prolonged-release)

Take with or without food.

rilpivirine (Edurant)

Take with a meal.

Protease inhibitors

 

Food requirements

atazanavir (Reyataz) (taken with a booster dose of ritonavir or cobicistat)

Take with or after food (within two hours after a main meal or within half an hour after a snack).

darunavir (Prezista) (always taken with a booster dose of ritonavir or cobicistat)

Take with or after food (within half an hour after a meal).

fosamprenavir (Telzir) (usually taken with ritonavir)

May be taken with or without food.

lopinavir/ritonavir (Kaletra)

Take with or without food.

ritonavir (Norvir)

May be taken with or after food, but taking with a fatty meal minimises the risk of nausea (this is less of a problem with the low dose [100mg] of ritonavir taken as a booster for other protease inhibitors).

tipranavir (Aptivus) (must be taken with ritonavir)

Take with or after food to reduce the incidence of side-effects.

Fusion and entry inhibitors

 

Food requirements

maraviroc (Celsentri)

May be taken with or without food.

enfuvirtide (Fuzeon)

Administered by injection. No food restrictions.

Integrase inhibitors

 

Food requirements

dolutegravir (Tivicay)

May be taken with or without food. If you have some resistance to integrase inhibitors, you will be asked to take it with food.

raltegravir (Isentress)

May be taken with or without food. Do not chew, crush or split tablets.

Share this